Careers
Great people form the core of any great organization. PreludeDx is always looking for highly qualified people with a passion for improving the lives of cancer patients. We will periodically post information about openings but are always interested in hearing from those who believe in our mission and values.
For more information, contact: careers@preludedx.com
Open Positions
Job Title: Operations Manager
Department: Operations / Clinical Laboratory / Customer Care
Reports To: SVP Operations
Location: Harrisburg, Pennsylvania
JOB PURPOSE
The Operations Senior Manager oversees the daily performance, quality, and efficiency of the Clinical Laboratory and Customer Care departments. This role ensures compliant laboratory operations, accurate sample processing, exceptional customer service, and seamless coordination across teams. The Operations Manager drives operational excellence, maintains regulatory adherence, and supports both client-facing and technical functions to ensure optimal patient and customer outcomes.
KEY RESPONSIBILITIES
Operational Leadership
- Manage day‑to‑day activities in the clinical laboratory, customer care, and operations areas.
- Develop, monitor, and optimize workflow processes, ensuring smooth lab and customer support operations.
- Oversee Laboratory Information Systems (LIS) performance, enhancements, and troubleshooting.
- Ensure compliance with CLIA, CAP, Federal Regulations, and internal policies.
- Assist in resource planning, budgeting, and performance tracking.
- Evaluate overall performance by gathering, analyzing and interpreting data and metrics
- Provides leadership to supervisors and staff in the implementation of new processes and techniques. Collaborates with Laboratory and Medical Directors, as well as external stakeholders in establishing strategic plans and development of new programs to improve efficiency, quality, compliance, service and financial outcomes for the laboratories.
Laboratory Oversight
- In collaboration and consultation with the medical director and administrative director manages the entire anatomic pathology operation.
- Manages all histology/pathology activities, including recruiting, hiring and training of staff.
- Supervise all phases of laboratory testing (pre‑analytic, analytic, post‑analytic).
- Ensure quality control, documentation accuracy, and compliance with accrediting bodies.
- Oversee method validation, new test implementation, and SOP development or revision.
- Support troubleshooting, maintenance, and calibration of laboratory instruments.
- Evaluate and review lab results, QC data, and proficiency testing variances, ensuring corrective actions are implemented.
Customer Care & Client Support
- Lead the customer care team in managing phone support, client inquiries, and service escalation.
- Ensure timely distribution of patient reports through various communication channels.
- Support sample tracking, data entry, and retrieval of missing patient information.
- Coordinate client-facing communications and service recovery activities.
- Maintain strong relationships with sales, clients, and internal stakeholders.
Staff Leadership & Training
- Supervise laboratory and customer care staff, fostering collaboration and continuous improvement.
- Provide coaching, performance feedback, and training.
- Manage scheduling, staffing, and onboarding processes.
- Promote team communication, professionalism, and adherence to company standards.
Project & Continuous Improvement
- Partner with project managers and scientists on development, testing, and operational initiatives.
- Participate in project meetings and ensure documentation requirements are met.
- Identify opportunities for workflow enhancements, cost-effectiveness, and operational efficiency.
Reporting & Documentation
- Prepare operational, performance, and quality metrics reports.
- Maintain accurate documentation in accordance with CLIA/CAP and company requirements.
- Utilize Excel, LIS, CRM, and other systems to support reporting needs.
Other Duties
- Maintain a clean and safe work environment and enforce company safety protocols.
- Ensure adequate inventory and cost-effective utilization of resources.
- Perform additional duties as assigned.
REQUIRED SKILLS & QUALIFICATIONS
- Bachelor’s degree in Life Sciences, Business, or related field (Master’s preferred).
- 7+ years of clinical laboratory operations experience in a CLIA/CAP environment.
- Experience leading teams in fast‑paced, regulated environments.
- Knowledge of immunohistochemical staining, tissue sections, and automated immuno-stainers.
- Strong communication, analytical, organizational, and problem‑solving skills.
- Proficiency in Microsoft Office Suite; familiarity with LIS, CRM, and ERP systems.
- High attention to detail, accuracy, and adaptability.
- Demonstrated ability to provide excellent customer service and support.
- Ability to lift up to 10 pounds; must pass color vision test (for technical tasks).
TRAVEL REQUIRED
- Possibly
ABOUT PRELUDEDX
PreludeDx is an Innovative Healthcare company and leading personalized breast cancer diagnostics company dedicated to serving breast cancer patients and physicians worldwide. Founded in 2009 with technology licensed from University of California San Francisco, PreludeDx has focused on developing precision breast cancer tools that will impact a patient’s treatment decision. Our mission is to provide patients and physicians with innovative technologies that improve patient outcomes and reduce the overall cost burden to the healthcare system. Before making a treatment decision, Know Your Risk™.
Job Title: Laboratory Technician
Department: Anatomic Pathology
Reports To: Laboratory Manager
Location: Laguna Hills, CA
Hours: 1:00pm-9:30pm Tues-Sat.
Job Purpose
The Lab Tech is responsible for a multitude of pre-analytical and post-analytical support services in a high complexity testing CLIA certified laboratory.
Essential Responsibilities
- Prioritize and monitor cases throughout the day
- Routinely interface with Pathologists
- Troubleshoot missing or delayed cases
- Provide status updates of cases as required
- Ensure that all actions taken on behalf of a client or a patient are appropriately documented in the current information systems and are according to standard operating procedures’
- Support services for the laboratory, sales and clients
- Responsible for client services duties as assigned by the supervisor
- Label, scan slides and prepare slide boxes for shipment
- Maintain organized pathology reports
- Responsible for specimen accessioning and data entry in the LIS
- Responsible for logistics duties as assigned by the supervisor
- Use personal protective equipment appropriately and demonstrate safe work practices in accordance with laboratory and company policy. Maintain a clean and safe work environment
- Demonstrate excellent customer service skills
- Organize and file slides that have been stained and reviewed
- Extract and synthesize clinical data from pathology reports into format that can be used in a clinical database
- Performs other duties as assigned
The above list represents the general duties considered essential functions of the job and is not to be considered an exhaustive description of all the work requirements that may be inherent in the position.
Requirements
- Knowledge of Histotechnology and Immunohistochemistry in a clinical setting
- High School Diploma required
- Associate’s Degree or Bachelor’s Degree preferred
- Working knowledge of MS Office
- Ability to adapt to changing procedures, policies and work environment
- Good data entry skills
- Ability to communicate effectively and follow written and verbal instructions
- High level of accuracy and attention to detail
- Ability to work in a fast paced team environment
- Ability to multitask and prioritize with little supervision
ABOUT PRELUDEDX
PreludeDx is an Innovative Healthcare company and leading personalized breast cancer diagnostics company dedicated to serving breast cancer patients and physicians worldwide. Founded in 2009 with technology licensed from University of California San Francisco, PreludeDx has focused on developing precision breast cancer tools that will impact a patient’s treatment decision. Our mission is to provide patients and physicians with innovative technologies that improve patient outcomes and reduce the overall cost burden to the healthcare system. Before making a treatment decision, Know Your Risk™.
Job Title: Customer Care Representative I
Department: Lab Operations
Reports To: Customer Care Manager
Location: Harrisburg, PA
Compensation: $18-20/hr
Hours: 11am -7:30pm M-F
DESCRIPTION
The primary objective of the Customer Care Representative I is to deliver exceptional customer service by efficiently addressing client inquiries and retrieving missing information. This role also involves accurately receiving, verifying, prioritizing, and facilitating the tracking of patient samples within the lab. Additionally, the representative ensures timely distribution of patient results and coordinates the return of samples to clients.
ESSENTIAL RESPONSIBILITIES
- Provide exemplary customer service.
- Receive packages.
- Utilize excellent verbal and written communication skills in order to coordinate with subjects, team members, other departments and outside institutions.
- Answer phones, route calls appropriately, greet visitors in a courteous manner.
- Assist sales team/clients with questions and obtaining patient results.
- Accessioning & data entry.
- Track internal and external samples.
- Organize and assist in the retrieval of missing patient information.
- Responsible for faxing and mailing patient reports in a timely manner.
- Filing as needed.
- Prepare detailed Excel reports.
- Maintain an organized work area.
The above list represents the general duties considered essential functions of the job and is not to be considered an exhaustive description of all the work requirements that may be inherent in the position.
REQUIREMENTS
- High School Diploma required.
- Bachelor’s in Biology, Biological Science, Chemistry preferred.
- Laboratory experience or strong interest preferred.
- Strong attention to detail, interpersonal skills.
- Ability to multi-task in a fast-paced environment while working independently with a diverse subject population.
- Requires strong computer and organizational skills and the ability to prioritize shifting work demands.
- Requires proficiency in Microsoft Office suite of programs including Word, Excel and PowerPoint.
- Ability to work well independently, complete projects in a timely manner, and prioritize multiple projects to ensure the completion of essential tasks by deadlines.
- Knowledge of querying and solid analytical skills with ability to compile data from many sources and define designs to use data.
ABOUT PRELUDEDX
PreludeDx is an Innovative Healthcare company and leading personalized breast cancer diagnostics company dedicated to serving breast cancer patients and physicians worldwide. Founded in 2009 with technology licensed from University of California San Francisco, PreludeDx has focused on developing precision breast cancer tools that will impact a patient’s treatment decision. Our mission is to provide patients and physicians with innovative technologies that improve patient outcomes and reduce the overall cost burden to the healthcare system. Before making a treatment decision, Know Your Risk™.
Job Title: Customer Care Representative I
Department: Lab Operations
Reports To: Customer Care Manager
Location: Laguna Hills, CA
Compensation: $20-25/hr
Hours: 9am-5:30pm M-F
DESCRIPTION
The primary objective of the Customer Care Representative I is to deliver exceptional customer service by efficiently addressing client inquiries and retrieving missing information. This role also involves accurately receiving, verifying, prioritizing, and facilitating the tracking of patient samples within the lab. Additionally, the representative ensures timely distribution of patient results and coordinates the return of samples to clients.
ESSENTIAL RESPONSIBILITIES
- Provide exemplary customer service.
- Receive packages.
- Utilize excellent verbal and written communication skills in order to coordinate with subjects, team members, other departments and outside institutions.
- Answer phones, route calls appropriately, greet visitors in a courteous manner.
- Assist sales team/clients with questions and obtaining patient results.
- Accessioning & data entry.
- Track internal and external samples.
- Organize and assist in the retrieval of missing patient information.
- Responsible for faxing and mailing patient reports in a timely manner.
- Filing as needed.
- Prepare detailed Excel reports.
- Maintain an organized work area.
The above list represents the general duties considered essential functions of the job and is not to be considered an exhaustive description of all the work requirements that may be inherent in the position.
REQUIREMENTS
- High School Diploma required.
- Bachelor’s in Biology, Biological Science, Chemistry preferred.
- Laboratory experience or strong interest preferred.
- Strong attention to detail, interpersonal skills.
- Ability to multi-task in a fast-paced environment while working independently with a diverse subject population.
- Requires strong computer and organizational skills and the ability to prioritize shifting work demands.
- Requires proficiency in Microsoft Office suite of programs including Word, Excel and PowerPoint.
- Ability to work well independently, complete projects in a timely manner, and prioritize multiple projects to ensure the completion of essential tasks by deadlines.
- Knowledge of querying and solid analytical skills with ability to compile data from many sources and define designs to use data.
ABOUT PRELUDEDX
PreludeDx is an Innovative Healthcare company and leading personalized breast cancer diagnostics company dedicated to serving breast cancer patients and physicians worldwide. Founded in 2009 with technology licensed from University of California San Francisco, PreludeDx has focused on developing precision breast cancer tools that will impact a patient’s treatment decision. Our mission is to provide patients and physicians with innovative technologies that improve patient outcomes and reduce the overall cost burden to the healthcare system. Before making a treatment decision, Know Your Risk™.
Job Title: Medical Science Liaison
Department: Medical Affairs (Sales & Marketing)
Reports To: VP Global Medical Affairs
Location: Remote – New Jersey, Philadelphia, Chicago, Dallas, or Los Angeles
Hours: 8am-5pm M-F
JOB PURPOSE:
The Medical Science Liaison is a customer-facing position and a critical member of both the PreludeDx commercial & clinical teams. You will be responsible for delivering key messages, presenting complex data, providing on-site customer service and education, providing critical feedback as well as addressing customer challenges to maximize adoption in key accounts. You will build and maintain a comprehensive understanding of your customers and support our commercialization efforts.
You will be the clinical face of DCISionRT, the only test available that is both predictive and prognostic regarding recurrence and radiation benefit for patients diagnosed with DCIS.
Ideally, you will have extensive experience communicating complex information in breast cancer, both in the Invasive and DCIS disciplines, and will have pharmaceutical or molecular diagnostic industry experience.
ESSENTIAL RESPONSIBILITIES:
Key Account Development
- Build, manage, and maintain relationships with key accounts within our customer base
- Be an ambassador for the brand; demonstrate in-depth knowledge of PreludeDx, its vision, and our products
- Educate and inform clinicians and other decision-makers through the presentation of complex scientific ideas relevant to the intersection between the fields of oncology and genomics
- Establish a linkage between PreludeDx technologies and existing challenges in the clinic
- Identify, develop, and maintain professional relationships with thought leaders, researchers, and healthcare professionals in breast cancer to ensure communication of current and emerging scientific information resulting in the appropriate use of the product
- Collaborate with commercial, marketing, and R&D teams in the scientific aspects of current and future products
- Support internal training initiatives
- Gather market intelligence for new product development and research opportunities
- Participate in the strategic planning development, and writing of clinical abstracts, manuscripts, and study protocols
Clinical Expertise
- Provide scientific exchange to Physician Groups, Integrated Health Systems, Strategic Accounts, Academic Medical Centers, payors, commercial managed markets, and related healthcare organizations
- Maintain clinical, scientific, and technical expertise in the breast cancer & genomics arenas; interpret and effectively communicate relevant topics
- Provide scientific support during medical conferences, meetings and trade shows
- Assist in the development and organization of local key opinion leader groups
Internal Collaboration & Knowledge Sharing
- Provide strategic input as a member of cross-functional teams
- Impart key customer insights to business partners with proposed business solutions to help guide strategic direction within the assigned region
- Provide clinical input and training to commercial functions within regulatory guidelines
- Assist with content development and scientific review of presentations and promotional materials upon request.
- Analyze data and write abstracts, posters, and presentations for submission and publication
The above list represents the general duties considered essential functions of the job and is not to be considered an exhaustive description of all the work requirements that may be inherent in the position.
POSITION REQUIREMENTS:
- Experience in breast cancer and/or cancer genomics is preferred, clinical or biotech industry experience also considered
- Experience with prognostic or predictive assays is a plus
- Experience in analyzing data and writing abstracts for submission and publication
- Strong written and oral communication and interpersonal skills
- Proven key account management skills
- Working knowledge, training or clinical experience in genomics, molecular biology or breast cancer is a plus
- Established breast cancer contacts in specific geographies is a plus
- Proven Project Management, planning and organizational skills
- Ability to work in PowerPoint to produce/edit presentations
- Willingness to travel, up to 70%
EDUCATION:
MD/DO, PhD, PharmD, PA/NP with clinical or translational biomarker experience in oncology (doctoral preferred)
ABOUT PRELUDEDX
PreludeDx is an Innovative Healthcare company and leading personalized breast cancer diagnostics company dedicated to serving breast cancer patients and physicians worldwide. Founded in 2009 with technology licensed from University of California San Francisco, PreludeDx has focused on developing precision breast cancer tools that will impact a patient’s treatment decision. Our mission is to provide patients and physicians with innovative technologies that improve patient outcomes and reduce the overall cost burden to the healthcare system. Before making a treatment decision, Know Your Risk™.
Job Title: Head of Revenue Cycle
Department: Revenue Cycle
Reports To: CFO
Location: Laguna Hills, CA (onsite)
Compensation: $145,000-$190,000 annual base + bonus
Hours: 8am-5pm M-F
Job Summary:
As an experienced Head of Revenue Cycle Management reporting to our CFO, you will be working in a fast-paced, rapidly growing environment where you will be relied on for your expertise, professionalism, and collaboration.
Essential Responsibilities:
- Drive Strategic planning to deliver scalable, evolving solution to meet developing demands in Revenue Cycle Management
- Lead day-to-day revenue cycle operations, overseeing the following teams: authorization, eligibility & benefit verification, billing, A/R, denials management and payment posting.
- Drive operational excellence and accountability through a metrics driven culture conducting daily, weekly, monthly, quarterly, and annual analysis of Key Performance Indicators (KPIs)
- Coordinates efforts amongst cross functional teams including operations, finance, and IT to ensure alignment with RCM goals and metrics
- Develops long-range strategic plans for systems and processes that support a high performing, patient-centered revenue cycle
- Lead initiatives to resolve problematic trends and resolve difficult account issues as needed
- Maintain appropriate internal control safeguards over A/R records and collection of cash and monitor compliance standards for providing accurate information on all system billings
- Understands and stays abreast of payer requirements and changes in the industry and communicates those changes as well as the financial impact to leadership
- Drive and manage the development of performance metrics, goal setting and support the development of RCM organizational structure, including the selection, direction and ongoing development of teams fostering a positive work environment
The above list represents the general duties considered essential functions of the job and is not to be considered an exhaustive description of all the work requirements that may be inherent in the position.
Position Requirements:
- Bachelor’s degree in Business Administration, Health, Finance or related field. Extensive experience may substitute for education.
- Ten (10) years progressive experience in laboratory healthcare management in a Revenue Cycle or Financial Leadership role including billing and collections.
- Dynamic, with the capacity to successfully manage many projects and responsibilities.
- Team builder with excellent interpersonal skills.
ABOUT PRELUDEDX
PreludeDx is an Innovative Healthcare company and leading personalized breast cancer diagnostics company dedicated to serving breast cancer patients and physicians worldwide. Founded in 2009 with technology licensed from University of California San Francisco, PreludeDx has focused on developing precision breast cancer tools that will impact a patient’s treatment decision. Our mission is to provide patients and physicians with innovative technologies that improve patient outcomes and reduce the overall cost burden to the healthcare system. Before making a treatment decision, Know Your Risk™.
Job Title: Medical Biller/Collector
Department: Revenue Cycle
Reports To: Director, Revenue Cycle Management
Location: Laguna Hills, CA (onsite)
Compensation: $28-30/hr
Hours: 8am-5pm M-F
Description
This position will perform collections and medical billing for various regional and national payers, including Federal, State, Third Party (HMO, PPO, IPA, TPA Indemnity) and Patient Billing. Qualified candidates must be able to (1) Review accounts for billing accuracy in order to maximize reimbursement. (2) Persuasive and tenacious follow-up on claims status (3) Appeal, and re-bill or forward claims for recalculation and / or adjudication as necessary. Must possess detailed knowledge of all medical benefit levels and have a thorough understanding of Federal, State, PPO, HMO, and Indemnity Plans structure. Must meet or exceed the standard level of performance on assigned accounts.
ESSENTIAL RESPONSIBILITIES
- Data entry, correct insurance assignment to patient accounts, insurance eligibility verification. Review/update demographics and patient information for accuracy.
- Working knowledge of appropriate coding systems; CPT, ICD-9 and HCPCS, coverage; LCD/NCD and reimbursement associated with such codes.
- Processing, validation of payer requests and processed claims via correspondence, remittance advice and EOBs (i.e., identification of payment discrepancies, inappropriate requests)
- Investigate all denied services to determine the reason for the service denial, appeal, if appropriate. Identify, report root causes associated with denials
- Timely, effective processing of assigned appeals including development, submission, tracking, reporting and evaluation of appeal outcomes (i.e., next steps, improved outcomes)
- Maximize utilization of Billing system, tools, and resources to support cash collection activities.
- Review and work various reports including aging, adjustments and credit balances.
- Comply with Federal and State legislation pertaining to all billing related matters.
- Comply with all Safety, Emergency, Hazard, OSHA, HIPAA, Quality Assurance and Administrative Plans, Policies, Guidelines, Protocol, and Standards.
- Support and maintain department cash and DSO goals
- Other duties as assigned
The above list represents the general duties considered essential functions of the job and is not to be considered an exhaustive description of all the work requirements that may be inherent in the position.
Requirements
High School Diploma and a minimum of four years related experience or a Bachelor’s degree from a four-year college or university; or equivalent combination of education and experience
- Working knowledge and prior hands-on experience of medical billing and reimbursement. Proficient in Microsoft Outlook, Excel, Word, the Inter and Intranet and other programs/software as necessary.
- Problem solving skills, using good judgment, attention to detail and follow-through are a must.
- Excellent customer service skills; excellent verbal and written communication skills. Ability to prioritize work, multi-task and time management skills.
- Support cross-trained culture
- Excellent troubleshooting and time management skills, attention to detail, utilizes time in constructive manner
- Ability to easily adapt to increased business demands
- Ability to effectively work with and resolve complex accounts & billing issues
- Self-starter, ability to work independently
- Flexible and reliable
- Ability to effectively prioritize and multi-task
- Ability to work in fast paced environment, perform under pressure, meet tight timelines
- Establish and maintain cohesive and good working relationships.
- Excellent communication and customer service skills; cooperative, work collaboratively and treat others in respectful, professional and supportive manner.
ABOUT PRELUDEDX
PreludeDx is an Innovative Healthcare company and leading personalized breast cancer diagnostics company dedicated to serving breast cancer patients and physicians worldwide. Founded in 2009 with technology licensed from University of California San Francisco, PreludeDx has focused on developing precision breast cancer tools that will impact a patient’s treatment decision. Our mission is to provide patients and physicians with innovative technologies that improve patient outcomes and reduce the overall cost burden to the healthcare system. Before making a treatment decision, Know Your Risk™.
Job Title: QA Manager
Department: Regulatory Affairs & Quality
Reports To: Sr. Director, Regulatory Affairs & Quality
Location: Laguna Hills, CA (onsite)
Compensation: $90,000-$150,000 per year
Hours: 8am to 5pm, Monday – Friday
JOB PURPOSE:
Responsible for monitoring the pre-analytical, analytical and post analytical process of the clinical laboratory services and ensuring compliance with regulatory, state and accreditation requirements.
Essential Responsibilities:
- Oversees, plans, coordinates, and manages quality assessment programs designed to ensure compliance with established standards of laboratory practice, CLIA, State regulations, CAP, and other laboratory accrediting agencies.
- Works with the Medical Director to oversee, plan, coordinate, and manage quality assessment programs.
- Includes the responsibility of directing all quality activities of all pre-examination, examination and post-examination phases in the laboratory.
- Responsible for managing all phases of Proficiency Testing activities at PreludeDx.
- Implement and oversee CAPA (Corrective and Preventative Actions), validations, inspections, document control, regulatory affairs, and problem resolution.
- Producing and/or overseeing the creation of documentation as it applies to quality assurance and regulatory affairs and manage document retention and control.
- Implements and maintains the web-based Document Control System at Prelude Dx.
- Act as the primary interface with external Quality Auditors and Regulatory Agencies during on-site audits, license and permit renewals, and follow-ups
- Coordinate and provide relevant documentation to Regulatory Agencies to enable timely product/ service registrations
- Responsible for the application and re-validation of Medicare licenses.
- Implementation of meaningful QA metrics for pre-analytical, analytical and post-analytical phases of laboratory testing.
- Responsible for presenting quarterly QMS metrics to management and staff.
- Responsible for ensuring adherence to environmental and safety protocols in compliance with State and Federal regulations
The above list represents the general duties considered essential functions of the job and is not to be considered an exhaustive description of all the work requirements that may be inherent in the position.
Position Requirements:
- Bachelors in Science Degree, MBA a plus
- Minimum 5 years of experience in clinical laboratory and quality positions.
ABOUT PRELUDEDX
PreludeDx is an Innovative Healthcare company and leading personalized breast cancer diagnostics company dedicated to serving breast cancer patients and physicians worldwide. Founded in 2009 with technology licensed from University of California San Francisco, PreludeDx has focused on developing precision breast cancer tools that will impact a patient’s treatment decision. Our mission is to provide patients and physicians with innovative technologies that improve patient outcomes and reduce the overall cost burden to the healthcare system. Before making a treatment decision, Know Your Risk™.
JOB TITLE: Clinical Laboratory Scientist
DEPARTMENT: R&D
REPORTS TO: CLS Manager
LOCATION: Laguna Hills, CA
COMPENSATION: 45-50/hour
HOURS: 8am to 5pm
JOB PURPOSE:
We are seeking a highly motivated and skilled licensed CLS to join our team. The ideal candidate will have experience in running Next Generation Sequencing (NGS) and knowledge of molecular biology techniques.
ESSENTIAL RESPONSIBILITIES:
- Ensure that the equipment is calibrated, maintained, and operated according to the manufacturer’s guidelines and standard operating procedures.
- Adheres to the CAP, CLIA and NYS regulations.
- Run protocols for sample collection, processing, storage, and tracking in LIMs to ensure the integrity and traceability of the samples throughout the NGS workflow.
- Run clinical and R&D samples for NGS and molecular biology techniques, including microdissection, FFPE nucleic acid extraction, NGS library preparation, sequencing, data analysis, and quality control measures with appropriate NGS controls.
- Perform and train other CLS’s on established NGS and molecular biology procedures, including macrodissection, FFPE nucleic acid extraction, NGS library preparation, sequencing, and data analysis, including quality control measures.
- Perform validation testing to ensure with selected reagents and controls to ensure the assay meets the required performance specifications.
- Perform validation studies to assess the performance characteristics of the NGS assay, including sensitivity, specificity, accuracy, precision, and reproducibility.
- Analyze and interpret data using appropriate statistical methods and software, including sensitivity, specificity, accuracy, precision and reproducibility.
- Maintain accurate records and documentation of experiments and results.
The above list represents the general duties considered essential functions of the job and is not to be considered an exhaustive description of all the work requirements that may be inherent in the position
POSITION REQUIREMENTS:
- Minimum 4 years as a certified or licensed clinical laboratory scientist
- California Clinical Laboratory Scientist (Highly Preferred: California Clinical Genetic Molecular Biologist Scientist license – CGMBS.)
- Must be well-organized, open-minded, decisive, and flexible. They must be able to communicate well with others, and work as a team. Good writing skills and and extensive computer experience are necessary
- Experience with Macrodissection, RNA extraction and downstream analysis
- Strong experience in development of targeted library, conducting sequencing NGS library preparation, sequencing, and data analysis
- Experience in project management and organization
- Excellent record-keeping and documentation skills
- Strong communication skills and ability to work in a team-oriented environment
- Validation and SOP writing experience a plus
- Must have superior work ethic, high energy level and be results oriented
- Internally motivated and self-starter; ability to make an impact
- Comfortable in a fast-paced environment
- Excellent oral and written communication skills
- Candidate must be a fast learner, naturally oriented toward problem solving, have superior work ethic, high energy level and be ambitious; good organizational skills
- Preferred Bachelor’s or Master’s degree in Molecular Biology, Biochemistry, or related field
- CLS license 4+ years
- Highly Preferred: California Clinical Genetic Molecular Biologist Scientist license – CGMBS
- Anatomic or Clinical Pathology experience
- Prior experience with NextGen sequencing instruments.
- Minimum of 4 years of molecular and histology experience within an anatomic pathology laboratory or clinical laboratory.
ABOUT PRELUDEDX
PreludeDx is an Innovative Healthcare company and leading personalized breast cancer diagnostics company dedicated to serving breast cancer patients and physicians worldwide. Founded in 2009 with technology licensed from University of California San Francisco, PreludeDx has focused on developing precision breast cancer tools that will impact a patient’s treatment decision. Our mission is to provide patients and physicians with innovative technologies that improve patient outcomes and reduce the overall cost burden to the healthcare system. Before making a treatment decision, Know Your Risk™.