Physicians Share How They Use DCISionRT in Clinic

The Clinical Impact of Precision Testing
on Your DCIS Patient Management

Presented by: Christy Kesslering, MD, Troy Bremer, Ph.D. and Jim Pellicane, MD

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Troy Bremer, Ph.D.

  • CSO and Founder of PreludeDx
2:00DCISionRT—Background of Assay, Supporting Evidence/Data, Outcomes

Jim Pellicane, MD

  • Breast Cancer Surgeon
  • Director of Breast Oncology
  • Bon Secours Cancer Institute
15:50Introduction
16:16Surgeon’s clinical dilemma to assessing risk in DCIS patients
22:57Why is ER not a good indicator of risk assessment?
24:13Why is patient age is no an independent predictor of risk?
25:23What are side effects of RT, especially for younger patients?
26:20What are the surgical options and decisions impacted by RT?
27:11Case Studies
36:00Personal lessons learned
39:18What is the impact of hormone therapy on DCISionRT score?

Christy Kesslering, MD

  • Radiation Oncologist, Breast Cancer Specialist
  • Radiation Oncology Consultants
  • Northwester Medicine Radiation Oncology, Warrenville
39:55Introduction
40:04Clinical dilemma: Am I seeing all the patients? When do surgeons refer patients to me?
50:04Why Tumor Grade and RTOG9804 Classification is not always the best indicator of Risk?
51:23Case Studies
52:15Clinical Application of DCISionRT testing for DCIS patients
53:08Why should DCISionRT be ordered for every patient?
55:20How genomic testing can help guide intensification and de-escalation of RT
56:52Challenges and solution insights for radiation oncologists to use genomics in DCIS

Q and A with the Panelists

59:22Why is 0.8 that DCISionRT common score? Answered by Christy
1:00:46Turn-around-time and Billing. Answered by Dr. Pellicane
1:01:43How do you build consensus/buy-in within your medical group/colleagues to implement a DCIS protocol between radiation oncologists and surgeons? Answered by Dr. Pellicane and Dr. Kesslering
1:03:20Why order DCISionRT on all my DCIS patients? Answered by Dr. Kesslering
1:04:28What are the results and implications of interaction studies between DCISion Score and RT? Answered by Dr. Bremer
105:59Conclusion

SHARE Cancer Support: DCIS Recurrence and Radiation

Narrator: Dr. Troy Bremer

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