Troy Bremer, PhD

Founder & Chief Scientific Officer of PreludeDx

0:05 Speaker Introduction and Agenda

Rachel Rabinovitch, MD, FASTRO

Radiation Oncologist, Professor, Radiation Oncology, University of Colorado

1:08 Background DCIS Treatment – Radiation Therapy Landmark Trials

Troy Bremer, PhD

Founder & Chief Scientific Officer of PreludeDx

10:35 Data Overview and Clinical Evidence
11:20 DCISionRT Test Report
12:39 Integration of Biology and Clinicopathologic Factors
16:50 DCISionRT Demonstrates Consistent RT Prediction
18:20 DCISionRT Correctly Reclassifies ClinPath in All Validation Cohorts
22:46 Supportive Evidence DCISionRT

Rachel Rabinovitch, MD, FASTRO

Radiation Oncologist, Professor, Radiation Oncology, University of Colorado

24:15 Clinical Application in Radiation Oncology – My Approach to DCIS

Panel Q and A Discussion

38:47 Q&A and Discussion
38:58 Test’s impact on mastectomy decisions
40:40 Risk assessment by ClinPath
42:05 Integrating into tumor board and workflow
42:58 Test’s impact on boost decisions
44:55 Test’s impact on margins assessment
51:19 DCISionRT vs OncotypeDCIS
52:40 ex-US availability
53:06 Getting started and specimen requirements
56:55 Test’s impact regarding endocrine therapy