Troy Bremer, Ph.D.

CSO and Founder of PreludeDx

0:46 Supportive evidence for DCISionRT
2:12 DCISionRT overview and test results
4:30 Validation data highlights
7:30 RT benefit prediction and NNT data highlight
8:14 Reclassification data highlight

Chirag Shah, MD

  • Radiation Oncologist
  • Director of Clinical Research and Associate Professor
  • Department of Radiation Oncology at the Cleveland Clinic
8:54 Introduction
9:07 Managing DCIS and RT role in background studies
12:30 Who needs or doesn’t need RT?
14:07 Changing treatment recommendations
15:51 Applying DCISionRT in my practice
17:11 Cost effectiveness and value
18:39 Case Studies
19:56 Conclusion: Radiation oncologist’s perspectives

Pat Whitworth, MD

  • Breast Surgical Oncology Specialist
  • St. Thomas Health, Ascension
  • Direction of Nashville Breast Center
21:06 Introduction
21:24 Impact of genomic testing in clinical practice, pre-op visit
22:43 Clinical dilemma for DCIS
24:33 DCIS tools to guide patient management, pros/cons
26:54 Surgical margins and guidelines
28:53 Genomic assays for DCIS
30:58 Identifying patients with RT benefit after BCS
31:58 Patient Discussion with DCISionRT Test Report
32:50 Clinical application and case studies
36:58 Conclusion: Surgeon’s perspectives
37:41 Decision impact PREDICT Registry

Q and A with the Panelists

38:50 How to interpret DCISionRT in context of ET?
39:48 Case study recommendation with low DCISionRT
42:10 Role of MSKCC nomogram for DCIS management?
43:40 DCISionRT protocol in own medical practices?
45:35 Role of APBI in DCIS?
46:48 Which patients are indicated for DCISionRT?