The Clinical Impact of Precision Testing on Your DCIS Patient Management
Presented by:
Christy Kesslering, MD
- Radiation Oncologist
- Breast Cancer Specialist
- Radiation Oncology Consultants
- Northwestern Medicine Radiation Oncology, Warrenville
Troy Bremer, Ph.D.
- CSO and Founder of PreludeDx
Jim Pellicane, MD
- Breast Cancer Surgeon
- Director of Breast Oncology
- Bon Secours Cancer Institute
Discussion Topic Time Stamps
Troy Bremer, Ph.D.
- CSO and Founder of PreludeDx
2:00 | DCISionRT—Background of Assay, Supporting Evidence/Data, Outcomes |
Jim Pellicane, MD
- Breast Cancer Surgeon
- Director of Breast Oncology
- Bon Secours Cancer Institute
15:50 | Introduction |
16:16 | Surgeon’s clinical dilemma to assessing risk in DCIS patients |
22:57 | Why is ER not a good indicator of risk assessment? |
24:13 | Why is patient age is no an independent predictor of risk? |
25:23 | What are side effects of RT, especially for younger patients? |
26:20 | What are the surgical options and decisions impacted by RT? |
27:11 | Case Studies |
36:00 | Personal lessons learned |
39:18 | What is the impact of hormone therapy on DCISionRT score? |
Christy Kesslering, MD
- Radiation Oncologist, Breast Cancer Specialist
- Radiation Oncology Consultants
- Northwester Medicine Radiation Oncology, Warrenville
39:55 | Introduction |
40:04 | Clinical dilemma: Am I seeing all the patients? When do surgeons refer patients to me? |
50:04 | Why Tumor Grade and RTOG9804 Classification is not always the best indicator of Risk? |
51:23 | Case Studies |
52:15 | Clinical Application of DCISionRT testing for DCIS patients |
53:08 | Why should DCISionRT be ordered for every patient? |
55:20 | How genomic testing can help guide intensification and de-escalation of RT |
56:52 | Challenges and solution insights for radiation oncologists to use genomics in DCIS |
Q and A with the Panelists
59:22 | Why is 0.8 that DCISionRT common score? Answered by Christy |
1:00:46 | Turn-around-time and Billing. Answered by Dr. Pellicane |
1:01:43 | How do you build consensus/buy-in within your medical group/colleagues to implement a DCIS protocol between radiation oncologists and surgeons? Answered by Dr. Pellicane and Dr. Kesslering |
1:03:20 | Why order DCISionRT on all my DCIS patients? Answered by Dr. Kesslering |
1:04:28 | What are the results and implications of interaction studies between DCISion Score and RT? Answered by Dr. Bremer |
105:59 | Conclusion |