What is your DCISion Score?

The Residual Risk Subtype (RRt) is a distinct molecular subtype identified by DCISionRT®. It represents patients with elevated recurrence risk after breast-conserving surgery (BCS) that is driven by the tumor’s underlying biology—not just traditional clinical factors.

DCISionRT generates a continuous Decision Score (0–10).

Different score ranges correspond to biologically distinct subtypes and levels of recurrence risk.

• A Decision Score of 9.2 uniquely defines the Residual Risk Subtype.
• 1 out of 5 DCIS patients are Residual Risk

A 9.2 Decision Score indicates:

• High residual biological risk after surgery
• Substantial likelihood of recurrence over 10 years without radiation
• Radiation therapy meaningfully reduces risk
• However, risk may remain elevated even after BCS + RT

Importantly, not all elevated scores represent RRt. Many elevated-risk patients derive substantial benefit from radiation and achieve strong risk reduction. RRt specifically identifies a unique group whose tumor biology may warrant broader treatment discussion.

The Residual Risk Subtype enables clinicians to align treatment intensity with tumor behavior, personalize adjuvant therapy recommendations, and support informed, shared decision-making with patients.